产品货号：
Z29961
中文名称：
VPRBP/DCAF1抗体
英文名称：
Anti-VPRBP/DCAF1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-VPRBP/DCAF1 Antibody |
| 指标别名 | DCAF1;HIV 1 Vpr binding protein;KIAA0800;Protein VPRBP;RIP;Vpr (HIV 1) binding protein;Vpr interacting protein;VPRBP |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM,ELISA |
| 基因名称 | DCAF1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human VPRBP/DCAF1 recombinant protein (Position:K540-K861). |
| 实际分子量 | 180KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | VprBP was first identified as a protein that can interact with HIV-1 viral protein R.It is a component of the CUL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex that could interact with HIV-1 virus Vpr protein and HIV-2 virus Vpx protein.VprBP is a 1,507-amino acid protein that contains conserved domains,including YXXY repeats,the Lis homology motif,and WD40 repeats.Through binding to Vpr,VprBP allows Vpr to modulate the catalytic activity of the CUL4-DDB1 complex,which in turn leads to the induction of G2 phase arrest in the virus-infected cells.Recently it has been reported that VprBP is able to regulate the p53-induced transcription and apoptotic pathway. |
| Uniprot ID | Q9Y4B6 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | DDB1 and CUL4 associated factor 1 |
| 蛋白名全称 | DDB1- and CUL4-associated factor 1 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells Enzyme linked immunosorbent assay (ELISA) 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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